Segment

Minutes

What happens

Why now

5

Open science follows the money, and the communities we work with

Part 1 · What open science is

10

A definition, the research life cycle, and the six pillars

Part 2 · Gold Standard Science

8

Nine federal tenets, matched to practices you already know

Part 3 · The 2026 landscape

5

Public access at acceptance, publication costs, CARE limits

Wrap-up

2

Five takeaways

Discussion

20

Six questions in pairs, one action each, report-out

REQUIRED

Public access at acceptance

NIH: every manuscript accepted on or after 1 July 2025 goes to PubMed Central with no embargo. DOE, EPA, USGS, NSF and USDA have equivalent policies.

FEDERAL FRAME

Gold Standard Science

Executive Order 14303 (23 May 2025) sets nine tenets. Agencies filed plans in August 2025 and first annual reports on 1 September 2026.

EXPECTED

Communities

People near Arizona-Sonora mine tailings, and Navajo Nation and Pueblo of Laguna communities near abandoned uranium mines, expect results shared with them.

ARIZONA

Arsenic in tailings dust

Findings about arsenic in mine-tailings dust and lung injury protect people only if health officials and residents can read them promptly: papers public at acceptance, protocols reproducible.

NEW MEXICO

Uranium and metal mixtures

UNM METALS Center data are collected with Navajo Nation and Pueblo of Laguna partners under community review. Openness means sharing on the community's terms, which is what CARE requires.

1 · PLANNING

Plan

Pre-registration and open protocols

2 · EXECUTION

Run

Open notebooks and transparent methods

3 · ANALYSIS

Analyze

Reproducible workflows and version control

4 · DISSEMINATION

Share

Open-access publishing and data sharing

Open access

Free to read. NIH is satisfied by the free accepted manuscript in PubMed Central; paid gold OA is optional.

Open data

Deposited with a persistent identifier, FAIR, within limits set by privacy, safety and CARE.

Open educational resources

Teaching and training materials under an open license such as CC BY.

Open methodology

Protocols, version-controlled code and pre-registered hypotheses and analysis plans.

Open peer review

Reviews signed, published or both; preprints reviewed before journal submission.

Open source software

Research software public under a recognized open license.

ARIZONA

Open methodology

Pre-registering the lung-injury endpoints for an arsenic-exposure mouse study fixes the outcomes before exposures begin, so selective reporting is off the table.

NEW MEXICO

Open data, as closed as necessary

A METALS biomonitoring dataset is shared with a DOI and full metadata, but chapter-level exposure values are released only with the community's authority, after NNHRRB approval.

23 MAY 2025

Executive order

EO 14303 sets nine tenets for every federal agency.

23 JUNE 2025

OSTP guidance

Applies to all agency-managed science, from selection through closeout.

22 AUG 2025

Agency plans

Implementation plans filed, including NIH's.

1 SEPT 2026

First reports

Agencies file their first annual progress reports.

Tenet (EO 14303 §3)

Open practice

What you do as a trainee

Reproducible

Open methodology, open source

Version your code; write protocols another lab can run

Transparent

Open data, open access

Deposit data with a DOI; the accepted manuscript to PMC

Communicative of error and uncertainty

Open methodology

Report intervals, detection limits and QA/QC, not only point estimates

Collaborative and interdisciplinary

Open data, open source

Use standard formats so the AZ and NM centers can compare

Skeptical of its findings

Open peer review

Post a preprint, invite critique, answer it in public

Structured for falsifiability

Pre-registration

Register hypotheses and endpoints before exposures begin

Subject to unbiased peer review

Open peer review

Review for others, declare conflicts

Accepting of negative results

Open data, preprints

Publish the null remediation trial and deposit its data

Without conflicts of interest

Transparency

Disclose funding and relationships in every output

WHAT NIH COMMITS TO

Training, compliance, replication

NIH's 22 August 2025 plan: more rigor and reproducibility training, stronger data-sharing compliance, support for replication studies, periodic public reporting.

1 · MOSTLY FAMILIAR

Partly new

Reviews (AIP FYI, SPARC) find the plans largely restate existing policy. New: annual reporting, AI tools to check reproducibility and bias, oversight of all funded research.

2 · CONTESTED

Follow the debate

The order gives political appointees a role in judging scientific integrity; critics in Science and SPARC warn this could constrain inquiry. Practice the tenets on their merits.

1 · AT ACCEPTANCE

Manuscript to PMC

Deposit the free accepted manuscript in PubMed Central at acceptance, no embargo. That satisfies NIH. No APC is required.

2 · IN THE BUDGET

Publication costs

NIH floated APC caps (NOT-OD-25-138). OMB's 29 May 2026 proposal would make publication costs unallowable unless pre-approved. Budget them explicitly.

3 · AS CLOSED AS NECESSARY

CARE and tribal review

Navajo Nation data need NNHRRB approval before collection and before release; Pueblo of Laguna has its own review. CARE governs.

1 · Six pillars

Open science is transparency, accessibility and collaboration across six pillars

2 · Nine tenets

Gold Standard Science renames those practices and attaches annual agency reporting

3 · At acceptance

Public access is required at acceptance; the free accepted manuscript is enough

4 · In the budget

Publication costs belong in every budget, because the rules on paying them are changing

5 · As closed as necessary

CARE and tribal review set the limits on openness

OPEN ACCESS

Will the accepted manuscript of your next paper go to PMC at acceptance, and who deposits it?

OPEN DATA

Could someone reuse your data from the repository record alone, without emailing you?

OPEN EDUCATIONAL RESOURCES

Have you shared a protocol, slide deck or exercise under an open license?

OPEN METHODOLOGY

Is your analysis code version-controlled? Have you ever pre-registered a study?

OPEN PEER REVIEW

Have you posted a preprint, or reviewed one in public?

OPEN SOURCE

Does your research software have a LICENSE file?

Create or complete an ORCID profile

Add publication costs as a budget line in your current proposal

Deposit your next accepted manuscript in PubMed Central yourself

Pre-register your next exposure study on OSF

Add a LICENSE file to your analysis code on GitHub

Ask whether your data involve tribal partners and need a CARE review

Question

Answer

True or false: every paper in Nature and Science is open access

False. They sell open access for a fee; the free accepted manuscript in PMC satisfies NIH.

Which tenet does pre-registration serve most directly?

Structured for falsifiability of hypotheses.

Do you need to pay an APC to comply with the NIH Public Access Policy?

No. Deposit the accepted manuscript in PMC at acceptance.